Solutions for the Pharmaceutical and Biotech Industries

• Organic Synthesis 
• Crystallization 
• Fermentation and Bio-Processing
• Process Development and Scale-up 
• Process Safety 
• Formulations and Product Development 
• Pilot Plant and Production Monitoring

In the early stages of chemical development, MiniBlock^® parallel reactor blocks offer the ability to screen and optimize liquid phase synthesis and solid phase synthesis routes. As the development process continues, reaction characterization and optimization can proceed to larger scale multiple vessel (EasyMax^TM, MultiMax^TM) and single vessel (LabMax^®, RC1e^TM) systems. All of our reactor systems are designed and manufactured to ensure safe and accurately controlled operation under a wide range of experimental conditions.

Real Time Analytics available for PAT monitoring include calorimetry (RC1e^TM, RTCal^TM), FTIR (ReactIR^TM) and particle characterization (FBRM^®, PVM^®). A common software platform (iC software) is available with most available instruments to simplify the execution and analysis of data rich experiments – freeing vast amounts of the researcher’s time allowing greater creativity and productivity.

The majority of industry specialty labs focused on Process Safety and Crystallization have embraced the reliability of METTLER TOLEDO solutions as standard methods in their development toolboxes.

PAT tools for FTIR reaction monitoring (MonARC^TM) and particle characterization (FBRM^®) are also available for monitoring in a GMP pilot plant or production environment, allowing knowledge developed at the laboratory scale to be used in a production setting for testing scale-up assumptions and ensuring batch to batch consistency in the manufacturing of API and formulated products.