METTLER TOLEDO
 

Improving Results in Thermal Analysis with Validation

Title page of validation handbookThe validation of equipment, processes and methods is a basic requirement in many industries.
It starts with equipment qualification, goes on to computerized system validation and ends with method validation.
The Validation Handbook is intended for newcomers and for thermal analysis practitioners interested in validating their equipment and methods.

Improve your result quality using current validation recommendations. Measurement results should reflect reality and hence serve as a basis for making decisions. Furthermore, you should be able to trust the result of a single measurement without the need to perform repeat measurements.
This handbook provides you with valuable inputs from the first idea to a validated method.
The handbook covers the following topics:
  • equipment qualification
  • computerized system validation
  • method validation
 
A strong focus is on measurement errors and uncertainty of measurements as well as on method validation in general. The method validation chapters cover the three possible ways:
  1. Analytical method validation
  2. Interlaboratory studies
  3. Standards (ASTM, ISO, DIN, …)
 
For the glass transition, the purity and the content determination, there are examples showing in detail how the theory can be applied to get a correct SOP and -finally- the validated method document.
 
In the Validation Handbook, the theory is always backed up with practical examples that demonstrate the benefit of validation.