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| Компания Sanofi-Aventis: Надежный технологический процесс благодаря системам динамического взвешивания МЕТТЛЕР ТОЛЕДО GARVENS Ни в одной отрасли производства необходимость контроля качества и надежности технологического процесса не является настолько критичной, как в фармацевтической. Sanofi-Aventis является мировым лидером производства препаратов для ключевых областей медицины: диабет/обмен веществ, сердечно-сосудистая система, тромбообразование, центральная нервная система, внутренние болезни, онкология и вакцинация для профилактики заболеваний. |
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| Analyzing Petroleum Wax According to ASTM D 4419 The ASTM D 4419 standard describes the conditions for measuring transition temperatures of petroleum waxes using differential calorimetry scanning (DSC). The transition temperatures provide petrochemical testing laboratories with important information on the quality of petroleum derivatives while the melting peak assists with the characterization and analysis of petroleum wax. |
| Analyzing the chewiness of gummy bears Gummy bears, like some other sweet snack foods, should be elastic, chewy and soluble. Product texture is influenced by the quality of the raw material (gelatin and sugars) and process and storage conditions. The results obtained with two branded gummy bears are discussed here in order to provide valuable information about product quality control, process optimization and transport and storage conditions for similar snack food products. |
| Liquid Fraction of Palm Oils Differential scanning calorimetry (DSC) is a powerful tool to characterize palm oil used in food products and for processing. The following example highlights how detailed information on crystallization and melting behavior can help maintain product quality. |
| Purity Determination of Drug Substances Drug substances have to be checked for purity as they are mostly used at purity levels greater than 99.9%. The check is frequently performed by HPLC although a further method is often necessary where High Performance Liquid Chromatography (HPLC) analysis is not suitable. In such cases, the DSC 1 differential scanning calorimeter offers a reliable alternative. |
| Reduced Storage Stability Testing Time Fulfilled by DSC The storage stability of cosmetic products is a key aspect for research and development, quality control and consumer satisfaction within the cosmetics industry. Due to the wide range of product forms and end use properties, the testing process can prove long and tedious. DSC offers a fast and yet reliable approach. |
| Thermal analysis used for pharmaceutical screening – Part 2 Polymorphism and pseudo-polymorphism are two phenomena that influence material properties. As mentioned in Part 1, polymorphic behavior in active ingredients is an important factor in the optimization of production and storage conditions. Thermal analysis techniques are widely used for screening samples, investigating crystallization processes and optimizing storage conditions to make sure that only the desired polymorphic form is present. Part 2 of this article deals with pseudo-polymorphism. The main issues are discussed and illustrated using glucose as an example. |